Symmetry breaking in human neuroblastoma cells
نویسندگان
چکیده
Asymmetric cell division (ACD) is a characteristic of cancer stem cells, which exhibit high malignant potential. However, the cellular mechanisms that regulate symmetric (self-renewal) and asymmetric cell divisions are mostly unknown. Using human neuroblastoma cells, we found that the oncosuppressor protein tripartite motif containing 32 (TRIM32) positively regulates ACD.
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عنوان ژورنال:
دوره 1 شماره
صفحات -
تاریخ انتشار 2014